Data-Driven Approaches to Fraud Detection in Health Insurance Claims: A Systematic Review of Medical and Pharmaceutical Services

Authors

DOI:

https://doi.org/10.61978/medicor.v4i2.1352

Keywords:

health insurance fraud detection, machine learning approaches, anomaly detection, healthcare claims analytics, medical and pharmaceutical services, systematic literature review

Abstract

Fraud in health insurance claims continues to impose significant financial and operational burdens on healthcare systems, especially as the volume and complexity of claims increase. Conventional rule-based detection mechanisms, although widely used, have limited adaptability to evolving fraud patterns and high-dimensional data environments. This limitation has driven a shift toward data-driven analytical approaches capable of identifying suspicious patterns more effectively. This systematic review synthesizes peer-reviewed, open-access studies published between 2020 and 2025 that applied rule-based, supervised, unsupervised, or hybrid methods for fraud detection in health insurance claims. A comprehensive search across major databases yielded fourteen eligible studies representing diverse systems, datasets, and methodological designs. The findings indicate a clear transition from traditional rule-based systems to machine learning approaches, particularly in addressing challenges such as label scarcity, class imbalance, and complex fraud patterns. Most studies focused on integrated medical claims, where pharmaceutical fraud was embedded rather than analyzed independently, highlighting a gap in service-specific research. Significant heterogeneity was observed in fraud definitions, preprocessing techniques, labeling strategies, and evaluation metrics, limiting cross-study comparability and emphasizing the need for greater methodological transparency. Across the literature, data-driven approaches are consistently positioned as decision-support tools rather than definitive solutions, reinforcing their role in complementing expert judgment and regulatory oversight. Overall, effective implementation requires context-aware design, reliable labeling, and rigorous real-world validation. Future research should prioritize domain-specific analyses, particularly in pharmaceutical fraud, and improve transparency to support scalable and responsible deployment.

Author Biography

Susi Ari, Universitas Gadjah Mada

Prof. Dr. Susi Ari Kristina, MPH, Pharmacist is a researcher and lecturer in the Management and Community Pharmacy Division, Pharmaceutics Department, Faculty of Pharmacy, at the Gadjah Mada University. Susi had been completed doctoral degree in Social, Economics, and Administrative Pharmacy at Mahidol University, Thailand in 2015. Susi is the instructor for social pharmacy, pharmaceutical management, and pharmacy informatics field for undergraduate and graduate curriculum. Her research interest was focus on public health pharmacy issues ranging from the cost of illness study, pharmacy practice, and pharmacy education. Her research articles have been published in international peer-reviewed journals including the topic of burden of diseases in Indonesia and Asian countries, availability and price of essential medicines, improving access of controlled medicines in Indonesia. Study on patient satisfaction, patient preferences, and willingness to pay for new pharmacy services is also in the interest. 

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Published

2026-04-22

How to Cite

Rukayah, S., & Kristina, S. A. (2026). Data-Driven Approaches to Fraud Detection in Health Insurance Claims: A Systematic Review of Medical and Pharmaceutical Services. Medicor : Journal of Health Informatics and Health Policy, 4(2), 75–84. https://doi.org/10.61978/medicor.v4i2.1352

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